Lipid Control with Choices. LOFIBRA® Fenofibrate Tablets and Capsules (Micronized)

LOFIBRA® Reduces Triglycerides and Increases HDLC-C2,4

LOFIBRA® belongs to a class of drugs called fibrates, which have been used for nearly a decade to help control lipids. According to the National Cholesterol Education Program, these drugs…

  • Reduce triglycerides by 20% to 50%.
  • Increase HDL-C by 10% to 20%.
  • Reduce LDL-C by 5% to 20%.

LOFIBRA® Is Used to Treat High Triglycerides

Along with a healthy diet and regular exercise, LOFIBRA® is used to treat adults with high triglycerides. When diet and exercise alone are not enough, your doctor may prescribe LOFIBRA® to lower triglycerides.

LOFIBRA® Is Also Used to Treat High LDL-C

LOFIBRA®, in addition to diet and exercise, is also used to lower low-density lipoprotein cholesterol (LDL-C), total cholesterol, and triglycerides in adults with high cholesterol or mixed lipid disorder.

LOFIBRA® Is Also Used to Treat Low HDL-C

Along with a healthy diet and regular exercise, LOFIBRA® is used to raise high-density lipoprotein cholesterol (HDL-C).

References

2. Executive Summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). JAMA. 2001;285(19):2486-2497.

4. National Cholesterol Education Program. National Heart, Lung, and Blood Institute. Live Healthier Live Longer: Cholesterol Counts for Everyone. Available at: http://www.nhlbi.nih.gov/chd/. Accessed November 7, 2005.

Indication

LOFIBRA® (fenofibrate capsules [micronized] and fenofibrate tablets) is a prescription medicine that, along with diet, reduces “bad” cholesterol (LDL) and triglycerides and increases “good” cholesterol (HDL) in your blood. While taking LOFIBRA®, a diet low in saturated fat and cholesterol should be followed. The long term effect of LOFIBRA® on cardiovascular events and mortality has not been determined.

Important Safety Information

The use of LOFIBRA® should be considered only when non-drug methods, such as diet, exercise, and weight loss, have failed to obtain satisfactory results.

Tell your doctor about all the medications you are taking. Some medications are known to cause an increase in triglycerides in the blood.

You should not take LOFIBRA® if you have severe kidney disease, have liver or gallbladder disease, are nursing, or are allergic to LOFIBRA®.

LOFIBRA® can cause liver or gallbladder problems. Your doctor may do blood tests to monitor your liver function or studies to check for gallstones.

Tell your doctor if you are taking any medications to slow the clotting of your blood (anticoagulants or blood thinners). LOFIBRA® may increase the effect of these medications, so your doctor may do frequent blood tests and may need to adjust your dose.

Call your doctor right away if you have unexplained muscle pain, tenderness, or weakness as these can be signs of a rare, but serious, side effect.

The most common side effects of LOFIBRA® are abdominal pain, abnormal liver tests, and respiratory symptoms.

Please see accompanying full prescribing information. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 800.FDA.1088.